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FDA-approved weight management medications beyond GLP-1 agonists include: Phentermine-topiramate (Qsymia): Combination sympathomimetic and anticonvulsant showing 8-10% weight loss in clinical trials

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Most individuals who follow a balanced diet get enough B12, but doctors may prescribe the shots for those who cannot absorb it.

The first step was designing an analogue of a biological medicine - a hormone called GLP-1, used in treatments for type 2 diabetes and obesity - that was inherently more stable in the harsh environment of the stomach