2011 Aug;61(8):732-6
The following table describes GLP-1 receptor agonists, their dosing frequency and key pharmacokinetic parameters: Cautions and Contraindications Adverse Effects Acute pancreatitis (rare) Injection site reactions Gastrointestinal disturbances (nausea, vomiting, diarrhoea dehydration and possible renal impairment) Increase in pancreatic enzymes: lipase and amylase (dulaglutide, tirzepatide and semaglutide) Cholecystitis and cholelithiasis Delayed gastric emptying (semaglutide, exenatide, dulaglutide, tirzepatide (diminishes over time)) Increased heart rate Diabetic retinopathy complications (semaglutide, particularly in insulin-treated patients with known diabetic retinopathy) Interactions GLP-1 receptor agonists do not interact via cytochrome P450 , but delayed gastric emptying may alter drug absorption
CON: Wegovy and Insurance Because Wegovy is specifically designed for weight loss, it is harder to get covered than Ozempic, making it very expensive
It can make sense for patients who have needle fatigue, injection site reactions, or anxiety around giving themselves shots every week, says Boca Raton, FL endocrinologist Sonia Gibson, MD
Every spring for the past five years, I lose about six weeks of my life to this misery
What happens when you mix Lexapro and caffeine
