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The injection site itself can develop minor redness, swelling, or tenderness in the first 24 to 48 hours after administration

It can soothe the stomach lining and improve gut motility, reducing the incidence and severity of gastrointestinal distress

Q5 Oral vs

These peptides havent been evaluated in pregnant or breastfeeding individuals, so their safety hasnt been established

The weight-loss effect of GLP-1RAs also benefits NASH improvement, by reducing appetite and increasing energy expenditure to promote weight loss, thereby indirectly ameliorating NASH

5.3 Challenges and innovations in therapeutic development Numerous glucagon receptor (GCGR)targeting compoundsincluding small molecules, monoclonal antibodies, and antisense oligonucleotideshave entered clinical development