"If paraxanthine is where all the benefits are, how long does it take when you're doing this drip-drop conversion to paraxanthine versus just giving paraxanthine and going right to the thing that works
Its mechanism involves modulation of the hypothalamic-pituitary-adrenal (HPA) axis, regulation of cortisol and growth hormone-releasing hormone (GHRH) secretion, and interaction with the GABAergic and glutamatergic systems
The other three linked pathways occur in mitochondria (i.e., cellular powerhouses)
Significant weight gain can create new fat deposits after liposuction or stretch out the skin after a tummy tuck
Neither is acceptable
Authors contributions GYW selected the topic, LDA, DCW and AT Acquired the data, LDA and AT drafted the manuscript, GYW, LDA and AT contributed critical revisions.