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To quantify total PDHc-E2 and OGDHc-E2, lipoate blots were stripped using Restore Western Blot Stripping Buffer (Thermo Fisher Scientific, 21059), reblocked in 5% skim milk in PBST and re-immunoblotted using appropriate primary antibodies

Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene

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Similarly, -KG competitors including succinate and itaconate inhibit the YBX1AMPK axis and sensitize cancer cells to glucose deprivation

Abstract Upon tissue damage the plant secondary metabolites glucosinolates can generate various hydrolysis products, including isothiocyanates (ITCs)