The GR inhibitor 2-Acetylamino-3-[4-(2-acetylamino-2-carboxy-ethylsulfanylthiocarbonylamino)phenylthiocarbamoylsulfanyl]propionic acid (2-AAPA) was prepared in DMSO, and then further diluted in MilliQ water and filter sterilised to produce a 1 mM stock solution
10.1210/mend.6.11.1480180 214 TillyJ
The list includes: Addisons disease Amyloidosis Ankylosing spondylitis Coeliac disease Crohns disease Dermatomysositis Graves disease Guillain-Barre syndrome Hashimotos thyroiditis Multiple sclerosis (MS-like presentation/SACD (subacute combined degeneration)) Myasthenia gravis Pernicious anaemia/B12 deficiency Reactive arthritis Restless leg syndrome (RLS) Rheumatoid arthritis Sjogrens syndrome Systemic lupus erythematosus Type 1 diabetes Ulcerative colitis Many of the above conditions have overlapping symptoms, for example fatigue, general ill-feeling, joint pain and rash
The subsections that follow discuss zinc, vitamin A, and pyridoxine, which are often used to treat symptoms other than delayed cognition in DS
Yan H, Ma Y, Liu M, Zhou L
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