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Acknowledgements The authors gratefully acknowledge the contributions of the NADIS consortium members: F.L

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CJC-1295 binds to GHRH receptors, increasing the baseline signal for growth hormone production Ipamorelin binds to ghrelin receptors, amplifying the pulse on top of CJC-1295's baseline elevation When both pathways are activated simultaneously, the growth hormone response is significantly greater than either peptide alone a true synergistic effect, not merely additive

Voluntary exercise and palatable high-fat diet both improve behavioural profile and stress responses in male rats exposed to early life stress: role of hippocampus