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Multi-center cohort studies document a 42.3% decline in sperm concentration and an 85.4% increase in sperm DNA fragmentation among men with elevated EED exposure

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In a familial form of amyotropic lateral sclerosis (ALS), a dominant gain-of-function mutation of the gene encoding superoxide dismutase (SOD) leads to production of reactive astrocytes of molecules that are toxic to motor neurons

Therefore, we estimate removal of this measure will decrease burden by approximately 14.2 hours (0.049 hours 289 cases) at a savings of $782 per HOPD (14.2 hours $55.06/hour)