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As a glucagon-like peptide-1 receptor agonist (GLP-1 RA), semaglutide exerts its effects through various mechanisms within the body

But it can lead to dry mouth, which might cause oral health problems

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Substantial Weight Reduction In a 48-week Phase 2 obesity trial, participants receiving retatrutide 12 mg once weekly reached an average 24.2% body weight reduction , with weight loss continuing through the study period rather than plateauing early

The Triple-Agonist Explained Before we dive into retatrutide dosage details, it is important to understand what this investigational compound is and how it works