retatrutide triple agonist glp-1 gip glucagon phase 3 2025 Today, we shared new data from two trials of retatrutide, our investigational agonist. Learn more at our link in bio Eli Lilly's retatrutide shows promising

These medications work by mimicking a naturally occurring hormone in the body called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels, slows gastric emptying, and increases feelings of fullness

That is not the goal

But when you swallow the drug, stomach enzymes dissolve some before your gut's mucosal lining can absorb and pass it to your bloodstream

I just have a negative association with eating, he tells WIRED

For those experiencing anxiety alongside their GLP-1 treatment , the digestive effects can sometimes amplify anxious feelings, particularly the social anxiety around potential embarrassing episodes

Both deliver the same active compound