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That translated to a relative risk of 1.34 and a number needed to harm (NNH) of approximately 4,500
Gastrointestinal side effects are the most common adverse events, which usually occur during the dose escalation period and then decrease over time
The conformation change in the receptor activates G proteins, a heterotrimeric protein with , , and subunits
Overlapping incretin effects could increase nausea, vomiting, dehydration, or glucose-management problems
[12] Ghrelin receptors, thought by researchers to regulate appetite, might, when activated, increase hunger cues
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