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[DOI] [PubMed] [Google Scholar] 65.Shimazu T, Matsushita H, Ishikawa K

This triggers the release of key satiety hormones including GLP-1, CCK and PYY, which work together to significantly reduce hunger, cravings, and caloric intake

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This inhibition facilitates NF-B nuclear translocation, driving the expression of proinflammatory cytokines (e.g., IL-8) and recruiting macrophages to inflamed tissues (92)