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Additionally, the deprivation or inhibition of glutamine has been observed to shift the metabolic state of glioblastoma U87MG cells towards glycolysis, accompanied by an up-regulation of the expression of the stemness marker CD133 [221]

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In its natural state, it is found in some fruits and vegetables, in plant and animal tissues, and in larger quantities it can be found in foods containing albumin

HO-1 is in charge of the oxidation of the heme groups free of ferrous iron (Fe2+), carbon monoxide, and biliverdin, the latter being reduced to bilirubin by biliverdin reductase, which acts as a fat-soluble antioxidant [32]