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Observations include mild injection-site reactions in some subjects

Since AD-like pathological lesions such as A deposition can be recognized in individuals with DS younger than 40 years old and symptoms of cognitive impairment due to AD exponentially increases from this age, DS has been regarded as a young model of AD 1,6,11

The PCA of the nine adjusted metabolite concentration values (glutathione, glutamate, and glutamine in each of the three voxels, ACC, Insula, and Visual) resulted in three components with an eigenvalue greater than 1

Acetyl-L-carnitine exerts protective effects against such neurotoxicity and oxidative stress.14

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