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PMID: 28831150 Guo XH (2016): The value of short- and long-acting glucagon-like peptide-1 agonists in the management of type 2 diabetes mellitus: experience with exenatide

This is where the story of skin bacteria comes in

As a footnote, the study was sponsored by Novo Nordisk

Your drug regimen may be adjusted over time, possibly to include a third drug and/or insulin, depending on how you respond to initial therapy

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In the next step, isocitrate dehydrogenase (IDH) metabolizes isocitrate to -ketoglutarate (-KG), which is further metabolized to succinyl-CoA by -KG dehydrogenase complex