In a landmark Phase 2 trial published in the New England Journal of Medicine, participants receiving the 12 mg dose experienced mean weight loss of 24.2% at 48 weeks, significantly exceeding results from earlier GLP-1 or dual-agonist therapies
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Strength gains are a reliable indicator that your muscle tissue is being preserved even as your overall weight decreases
10.1136/pgmj.2004.020057
Safety analysis Cardiovascular monitoring, heart rate increases, adverse event reporting
In several reported cases, symptoms improved following medication discontinuation, suggesting a potential causal relationship