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[5] [6] In women, obesity is linked to: Anovulation and irregular menstrual cycles : Excess adipose tissue produces oestrogen and inflammatory mediators that disrupt the hypothalamic-pituitary-ovarian axis, leading to irregular or absent ovulation

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A single fraction of 8 Gy has been shown to have similar benefits on bone pain relief and QOL as multiple fractions (3 Gy 10), as in the RTOG-9714 trial (NCT00003162).[52,53][Level of evidence A3] Evidence (palliation for bone metastases using strontium chloride): The use of radioisotopes such as 89Sr has been effective as palliative treatment of some patients with osteoblastic metastases

The policy stems from budget constraints, not medical evidence