The effects of SGLT2s inhibitors on hemodynamics and glomerular hyperfiltration seem to be robust whereas those of GLP-1RAs have not been established
Wang LL, Wang Q, Hong Y, Ojo O, Jiang Q, Hou YY, et al
The latter being the most important for adipose tissue remodelling
In the SURMOUNT clinical trial program for obesity, participants achieved average weight loss of 15-21% of body weight depending on dose, significantly exceeding results with diet and exercise alone or other available pharmacotherapies
If you are also working on digestion overall, these gut health strategies that support weight loss can make higher-protein meals easier to tolerate
Belwal, T., Bisht, A., Devkota, H