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NAC works mainly as an antioxidant, while NAD plays a key role in cellular metabolism and energy production

Steric hindrance is the major limiting factor in the synthesis of the B 12 coenzyme analogs

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Approximately 10% of ALS patients are hereditary, called familial ALS (fALS), while the remaining 90% (sALS) occur sporadically without apparent genetic predisposition (Van Daele et al., 2023)

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