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is supported by NIH research grant OT2OD032581 and a research grant from the American College of Clinical Pharmacy, reports consulting fees from Bayer AG, Sanofi, Boehringer Ingelheim, Eli Lilly and Proteomics International, reports payments for lectures from Dexcom and Med Learning Group and serves on the Board of Directors for the American Diabetes Association

In animal studies using spontaneously tumor-prone mice, Epithalon significantly reduced the frequency of malignant tumor development, inhibited tumor growth rates, and extended survival compared to untreated controls

The main difference is bioavailability at the target tissue

NAC, though widely used, has relatively low bioavailability, while NACA, due to its greater membrane permeability, can be used in lower concentrations and shows greater antioxidant potential

10.1093/toxsci/kfq039