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Also, as in the IMPACT trial, the skin and joint response was sustained through 50 weeks

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Conversely, NRF2 silencing reduces FSH-induced antioxidant gene expression and ROS scavenging [237]

It also has been described that -glutamylcysteine, the intermediate of GSH biosynthesis, is able to act as a Gpx1 cofactor in mitochondrial H 2 O 2 detoxification, mimicking the physiological properties of GSH (Quintana-Cabrera et al., 2012)

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