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10.1186/s13287-022-03161-y 79 MensahK

Realtime polymerase chain reaction reactions were performed in triplicate with iTaq Universal SYBR Green SuperMix (BioRad, California, USA) on Step One Plus thermocycler (Applied Biosystem, MA, USA)

B.Gonzalez-MaesoJ.et al (2022)

Another key role of glutathione is as an anti-oxidant and free radical scavenger role, particularly important in the mitochondria, where the catabolic conversion of nutrient substrates into carbon dioxide and water, with the concomitant recovery of chemical energy as ATP and of reductive power as NAD(P)H takes place

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RGN-352 was shown to be safe and well-tolerated with no serious drug-related adverse events reported (PMID: 20536472) Phase 2 AMI trial (incomplete): RegeneRx designed a Phase 2 proof-of-concept trial (NCT01311518) to evaluate RGN-352 in approximately 75 patients with acute ST-segment elevation myocardial infarction (heart attack)