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Gradual dose escalation minimizes gastrointestinal side effects such as nausea [4] [6]

doi: 10.1128/spectrum.01639-23 176 PooleJ.FosterE.ChalonerK.HuntJ.JenningsM

To achieve this, we established stable cell lines expressing Flag-tagged LCRMP-1 in CL1-0 cells and knocked down endogenous LCRMP-1 expression in CL1-5 or A549 cells using small-interference RNA (siRNA)

The micellar product produced greater baseline-adjusted blood exposure than the standard formulation under the study conditions

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