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If a person prefers an oral, research-backed supplement, Tonums Motus (oral) offers human clinical data showing measurable metabolic benefits

The disorder is caused by an autosomal recessive defect in ADSL (OMIM 608222), which encodes the enzyme ADSL involved in the de novo synthesis of purines

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Famularo G, Tzantzoglou S, Santini G, Trinchieri V, Moretti S, Koverech A, De Simone C

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Sometimes it develops after a single pregnancy as well