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However, high levels of MDA have been observed in both adults [115,116] and children with ADHD [117], and increased plasma MDA and urinary 8-OHdG levels were found in children with ADHD compared to healthy children [118]

Two phase 2 trials, including older adults up to 75 years, have recently been published assessing the impact of retatrutide on patients with overweight and obesity, with or without T2D, respectively [75, 118]

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For this indication, it is well established, with cardiovascular outcomes data to support its use

It may also help prevent side effects that sometimes happen when medication is stopped too quickly, such as increased hunger or digestive problems