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Mice with a deficiency of key components in the NF-B pathway die as a result of massive hepatocyte apoptosis induced by TNF 37,38 , supporting the critical role of maintenance of hepatocyte NF-B pathway in protecting against TNF cytotoxicity

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From the midline, 10 m serial sections were collected and stained with hematoxylin and eosin by the New York Medical College Histology Core

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