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GLP-1 RAs [sic] therapy may reduce the risk of dementia and Alzheimers disease in patients with CKD stage 3 or later, offering potential neuroprotective benefits beyond glycemic control, the researchers wrote

Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, et al

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Given that the heterogeneity of the reactive astrocyte profile depends on the level and duration of stress exposure, a single therapeutic approach is unlikely to be sufficient for treating multifactorial neurological diseases

Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: evidence for a marked somatotroph secretory capability in obesity