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Like other copper-binding tripeptides, its biological effects are proposed to occur through both the peptide backbone and the copper ion it coordinates with the copper contributing to enzymatic cofactor activity and oxidative stress modulation

H., Kim, S

This isn't arbitrary

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Researchers designed it to retain lipolytic (fat-reducing) properties while minimizing the broader systemic effects seen with full-length growth hormone

Lifetime residential and workplace exposure to environmental tobacco smoke and lung cancer in never-smoking women, Canada 1994-97