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doi: 10.1016/j.toxlet.2016.12.017 102 JungTBaderNGruneT

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The people at risk of getting low levels of B12 are: Vegans and vegetarians as its not in their diet Over 60s as they have reduced absorption within the gut Anti acid medication or metformin Chronic digestive disorders such as Crohns, celiac disease or IBS Eating disorders or people who have had weight loss surgery Drink alcohol or abuse nitrous oxide People who are HIV positive There are different types of synthetic vitamin B12

and those that regulate the level of lipid oxidation, reduce the production of intracellular antioxidant substances, and provide a favorable environment for high oxidation levels for ferroptosis

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If validated, this could expand our pharmacological toolkit beyond classical dopaminergic framings