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Unlike recombinant GH, CJC-1295 does not replace GH directly

The ClusPro 2.0 online server, which is a fully automated server engineered for proteinprotein docking simulations, was used to undertake a molecular docking analysis of the fusion proteins against human serum albumin (HSA) and the extracellular domain of the GLP-1 receptor (ECD-GLP-1R) 76

Another factor is the timeline of results

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The general rule for all GLP-1s: A dose taken within 48 hours of your usual scheduled day is acceptable for most people

It warrants clarification whether this effect holds true also in mice with more CNS-targeted deletion of GIPR and GLP-1R