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doi: 10.1016/j.diabres.2011.10.029 5 CosentinoFGrantPJAboyansVBaileyCJCerielloADelgadoVet al

In a second double-blind RCT, KET 0.5 mg/kg IV bolus followed by a 30 min infusion of 0.25 mg/kg/h increased mood and serum brain-derived neurotrophic factor, which is a marker of major depressive disorders and treatment response (Jiang et al., 2016)

Reducing appetite and signaling a sense of feeling full can help reduce "food noise" in the brain, leading people to think about (or obsess over) food less

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In contrast to insulin, however, GLP-1 causes a decrease in body weight [28]