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In chronic kidney disease, the pivotal FLOW trial demonstrated that semaglutide 1 mg reduced the risk of major kidney events by 24% in patients with type 2 diabetes and CKD, resulting in a dedicated indication in this population

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International Journal of Obesity, 46 (3), 449-465

Sarparast M, Pourmand E, Hinman J, Vonarx D, Reason T, Zhang F et al (2023) Dihydroxy-metabolites of dihomo-gamma-linolenic acid drive ferroptosis-mediated neurodegeneration