The results for many people have been remarkable: significant, sustained reduction in body weight, improved metabolic health, and a renewed sense of confidence and wellbeing
But retatrutide isn't FDA-approved yet, and the comparison is across different trials, not a head-to-head study
Avoid microbiome disruptors Certain dietary and lifestyle factors actively harm the bacteria you are trying to establish: Artificial sweeteners (sucralose and saccharin have been shown to negatively affect gut bacteria composition) Excessive alcohol (disrupts gut barrier integrity and kills beneficial bacteria) Highly processed foods (low in fiber, high in additives that harm microbial diversity) Unnecessary antibiotics (the single biggest destroyer of probiotic colonization) Chronic stress (documented effects on gut microbiome composition through the gut-brain axis) People who are working to optimize their metabolic health, whether through dietary modifications alongside GLP-1 medications or through natural approaches, should prioritize removing these disruptors alongside adding beneficial interventions
But no it's the extreme yo-yo that's harmful
Sometimes the body is not asking to be overridden
Those numbers are extraordinary