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On the contrary, -KG can be converted into glutamine through glutamate dehydrogenase (GDH) and glutamine synthetase (GS), or into CO 2 through the TCA cycle to provide energy to cells (58)

The authors suggested that the increase in pigments under stress with SL applications might be due to the decrease in SL-induced oxidative damage 86

No human clinical trials have been published as of 2026

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He added that Novo expects improvements in access and uptake among patients in the commercial insurance market, though the company is not giving any specific expectations