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muciniphila , induce GLP-1 secretion and improve glucose homeostasis in C57BL/6J mice fed a high-fat diet (HFD) through interaction with intercellular adhesion molecule 2 (Icam-2), which activates GPCR-like downstream signals

doi: 10.1016/j.dld.2010.01.016 186 BarbDPortillo-SanchezPCusiK

The ECD was reported to be relatively dynamic even in the presence of hormone peptide

Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity

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