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A similar approach was successfully applied to develop selective drug activators of the protein kinase AMPK, which were revealed to bind to an unexpected allosteric site on AMPK that is distinct from the canonical AMP-binding sites [213,214,215,216]

Biochem Biophys Rep

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Journal of Signal Transduction 2012, 2012 , 1-13

Vitamin B12 and folate both play important roles in energy metabolism, nervous system health, red blood cell production, and cognitive function

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