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GLP-1R agonists Several GLP-1R agonists, which mainly delay protease DPP-4 metabolism to overcome the problem with the rapid inactivation of GLP-1, have been developed (119)

The GLP-1RA group also had a 32% higher risk of excess weight gain (gaining more than recommended), a 30% higher risk of diabetes during pregnancy, a 29% higher risk of hypertensive disorders during pregnancy, and a 34% higher risk of preterm delivery

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