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This complex comprising TRF1, TRF2, POT1, TPP1, TIN2, and RAP1 serves a dual function: it protects chromosomal ends from being recognized as double-strand breaks by the DNA damage response machinery, and it regulates telomerase access to the telomere overhang

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Results Cysteine has a widespread protective effect under hypoxia in ovarian cancer cells Cysteine protected ES2 cells from death under hypoxia (H) after 16 h ( p = 0.026) (Fig