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For Dapagliflozin 21 pregnancies were reported of which 8 listed the corresponding pregnancy outcomes: 1 congenital hydrocephalus, 2 encephalocele, 1 non-healthy infant with talipes, renal aplasia and oesophageal atresia, 2 induced abortions, 1 healthy premature infant, 1 healthy infant

American Association of Clinical Endocrinology

Association between exposure to GLP-1 receptor agonists and risk of suicide-related and self-harm-related events

It is administered as a once-weekly subcutaneous injection with a defined dose-titration schedule

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Children metabolize tacrolimus more rapidly, so doses are often higher per kilogram of body weight, typically 0.15 to 0.3 mg/kg/day, divided twice daily