Over 100 GLP-1 therapies are currently in active development globally, with approximately 25 candidates in mid-to-late stage trials [41]
Plant Mol Biol 35(5):64154 Szklarczyk D, Santos A, Von Mering C, Jensen LJ, Bork P, Kuhn M (2016) STITCH 5: augmenting proteinchemical interaction networks with tissue and affinity data
In addition to obesity and diabetes, the condition GLP-1 drugs like semaglutide were initially tapped to treat, Wegovy now includes cardiovascular benefits on its label
GLP-1 is an incretin hormone that is secreted in response to food intake, and it exerts multiple actions conducive to glycemic control, including enhancing glucose-dependent insulin secretion, suppressing glucagon release, and delaying gastric emptying [39]
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