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Funding This work was supported by grants from Japan Society for the Promotion of Sciences (JSPS) [KAKENHI Grant Number: 26111004 (DY) and 20K19673 (LY)], and Grants for young researchers from Japan Association for Diabetes Education and Care (TK)
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In one large clinical trial, people taking tirzepatide lost an average of 15 to 20 percent of their starting body weight over 72 weeks
The follow up period used to examine outcomes irrespective of ongoing use of the medication (emulating a modified intention-to-treat analysis of a clinical trial), started from the index date, and continued until study end (October 30, 2021), death, or initiation of a GLP1-RA in the DPP4i group, whichever came first (Fig
doi: 10.1371/journal.pbio.0040365 62 BuckMDO'SullivanDKlein GeltinkRICurtisJDChangCHSaninDEet al
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