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John Brownstein, a study co-author and professor at Harvard Medical School, told ABC News "What we're seeing for the first time is that curve is bending and shows a sign of hope for something that was really a threat to American public health for so many years." A smaller survey by Gallup in 2025 confirmed that patient reported diagnoses of obesity have declined since a 2022 peak

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The simplest of these in vitro models is a monoculture of brain endothelial cells on transwell membrane inserts or standard flat tissue culture plates