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Bangalore S, Fayyad R, Laskey R, DeMicco DA, Messerli FH, Waters DD

Gastroenterology 141(1):150156

They reduce rosacea-associated erythema, papules, pustules, and eye symptoms

Patients with a personal or family history of medullary thyroid carcinoma or MEN2 syndrome should not use these medications at all

Cell migration and wound-closure assays (such as scratch assays in fibroblast or endothelial cell cultures) are standard in vitro models for studying this combination's proposed tissue-repair pathway effects, typically comparing single-compound versus combined-compound treatment conditions

Skin senescence displays a higher level of ApoD expression compared to young tissues, making this protein as a specific marker of aging