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Semaglutide reduces insulin requirements almost independent of weight loss in the early course of the treatment. In ADJUST-T1D, participants receiving semaglutide started the drug at a once-weekly 0.25 mg dose for 4 weeks, increasing to 0.5 mg at 4 weeks and 1 mg at 8 weeks for the remainder of the trial

CagriSema didnt meet the trials primary goal of proving that it could help people lose more weight than tirzepatide, which made headlines

Thats 80% of the equation

I looked into the GLP-1 pathway for a client around 1997-8 and thought it was an incredible opportunity, for diabetes that is- a fascinating mechanism including a safety valve that obviates hypoglycemia

PROMEC is funded by The Central Norway Regional Health Authority and the Research Council of Norway INFRASTRUKTUR programme (295910) (C.B.V.)

And you probably do not even know it