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The inhibition of the SLC7A5, SLC38A2 and SLC25A22 transporters may inhibit the uptake of glutamine in KRAS-mutant tumor cells, thereby inhibiting the growth and metabolism of tumor cells and achieving therapeutic effects [50]
Inoltre, riduce la produzione di glucagone, un ormone che favorisce il rilascio di glucosio da parte del fegato, e rallenta lo svuotamento gastrico, contribuendo al senso di saziet
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Results with GLP-1s can take time, especially since doses are titrated gradually
Endocrinology (2008) 149(2):5749.10.1210/en.2007-1292 24 Nuche-BerenguerBMorenoPPortal-NunezSDapiaSEsbritPVillanueva-PenacarrilloML