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The hypothalamic glucagon-like peptide 1 receptor is sufficient but not necessary for the regulation of energy balance and glucose homeostasis in mice

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The second is neural, where GLP-1 activates vagal nerve afferents in the gut wall that transmit satiety signals directly to the nucleus tractus solitarius (NTS) in the brainstem

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However, they can prepare by following the doctors instructions on medication, eating, and drinking before the procedure