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Patients should carefully follow dosing guidance from their prescribing clinician and compounding pharmacy and seek clarification immediately if dosing instructions are unclear

For 14 of 19 patients with an organic acidemia, TMAO levels were greater than 15 times the median level of the reference population (multiples of the median, MoM) with an overall average TMAO level in the organic acidemia cohort of 65 MoM ( p -value = 2.19 10 8 )

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