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Migraines and Headaches: B-complex vitamins, particularly riboflavin (B2) and pyridoxine (B6), have been associated with migraine prevention and reduction in headache frequency

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Aim The aim of the proposed protocol is to compare the effectiveness of orally and intramuscularly administered vitamin B12 in the normalisation of serum vitamin B12 concentrations at 8, 26 and 52 weeks of treatment, in patients aged 65 years with vitamin B12 deficiency treated at primary healthcare centres in the Madrid region, Spain