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Some preliminary Phase 1 studies may have explored even lower doses, like 1 mg, to establish initial safety, but the 2 mg dose was the starting point for the main dose-escalation study

Neuropathic pain phenotyping as a predictor of treatment response in painful diabetic neuropathy: data from the randomized, double-blind, COMBO-DN study

~H NMR, 60 MHz, D20, 6 ppm: 6.08 (s, 2 H, CH 2 ), 7.56 (s, 5 H, ~b), 7.939.22 (m, 4 H, pyr

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