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Biotransformation is a medical term that refers to ability to take compounds that are toxic or pollutant substances and then convert them into an end product that the body can eliminate with harm to the body

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Additionally, the presence of a mechanism in a petri dish or mouse model does not guarantee clinical relevance in humans

[5] This is the origin of sermorelins human evidence: a pediatric-endocrinology tool from the 1990s, later commercialized as Geref

While there has been much success within in vitro and animal models at the DNA and protein levels, there has yet to be successful translation of these therapeutics in human clinical trials